91滴滴

1. Analysis of biological samples and chemical analysis of environmental pollutants using separation techniques, including:

high-performance liquid chromatography (HPLC-MS/MS; HPLC-UV-Vis DAD; HPLC-FLD; HPLC-LSD), gas chromatography (GC-MS), capillary electrophoresis (CE-UV-Vis DAD).

2. Chemistry and biochemistry of thiol amino acids, homocysteine 鈥嬧�媡hiolactone and their metabolites.

3. Development of analytical methods enabling the determination of selected biologically important compounds in complex matrices.

4. Preparation of a biological sample for analysis; chemical derivatization.

5. Study of the possibilities of increasing sensitivity in capillary electrophoresis using concentration of analytes in the capillary.

Some publications:

1. A. Undas, J. Per艂a鈥慘aj谩n, R. 骋艂辞飞补肠办颈, Homocysteine in adult patients with cardiovascular disease: is it clinically relevant in 2025? A tribute to Hieronim Jakubowski, (1946鈥�2025), Polish Archives of Internal Medicine, 135 ( 2025) 1-8.

2. A. Krata, J. Domaga艂a, R. 骋艂辞飞补肠办颈, Hydrophilic interaction liquid chromatography based method for simultaneous determination of purines and their derivatives in food spices, Food Chemistry, 441 (2024) 138285.

3. J. Piechocka, R. 骋艂辞飞补肠办颈, Comprehensive studies on the development of HPLC-MS/MS and HPLC-FL based methods for routine determination of homocysteine thiolactone in human urine, Talanta, 272 (2024) 125791.

4. J. Piechocka, N. Matwiej, M. Gawe艂, M. Matyjaszczyk, R. 骋艂辞飞补肠办颈, G. Chwatko, Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine, Scientific Reports, 13 (2023) 20268.

5. J. Piechocka, R. 骋艂辞飞补肠办颈, One-pot sample preparation procedure for the determination of protein N-linked homocysteine by HPLC-FLD based method, J. Chromatogr. B, 1228 (2023) 123835.

6. J. Piechocka, M. Wyszczelska-Rokiel, R. 骋艂辞飞补肠办颈, Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method, Scientific Reports, 13 (2023) 9294, 1-12.

7. J. Piechocka, R. 骋艂辞飞补肠办颈, Up-to-date knowledge about analytical methods for homocysteine thiolactone determination in biological samples, Trends Anal. Chem. 鈥� TrAC, 159 (2023) 116906.

8. R. 骋艂辞飞补肠办颈, J. Piechocka, E. Bald, G. Chwatko, Application of Separation Techniques in Analytics of Biologically Relevant Sulfur Compounds, in Handbook of Bioanalytics (B. Buszewski, I. Baranowska (eds.)), Springer Nature, 2022, 233-256.

9. Bekier, J. Gatkowska, M. Chyb, J. Soko艂owska, G. Chwatko, R. 骋艂辞飞补肠办颈, A. Paneth, K. Dzitko, 4-Arylthiosemicarbazide derivatives 鈥� pharmacokinetics, toxicity and anti-Toxoplasma gondii activity in vivo, Eur. J. Med. Chem. 244 (2022) 114812.

10. J. Piechocka, M. Wieczorek, R. 骋艂辞飞补肠办颈, Gas Chromatography 鈥� Mass Spectrometry Based Approach For the Determination of Methionine 鈥� Related Sulfur Containing Compounds In Human Saliva, Int. J. Mol. Sci. 21, 2020, 9252.

11. J. Piechocka, M. Wro艅ska, R. 骋艂辞飞补肠办颈, Chromatographic strategies for the determination of aminothiols in human saliva, Trends Anal. Chem. 鈥� TrAC, 126 (2020) 115866.

12. J. Piechocka, M. Wro艅ska, G. Chwatko, H. Jakubowski, R. 骋艂辞飞补肠办颈, Quantification of homocysteine thiolactone in human saliva and urine by gas chromatography-mass spectrometry, J. Chromatogr. B. 1149 (2020) 122155.

13. J. Piechocka, M. Wro艅ska, I.E. G艂owacka, R. 骋艂辞飞补肠办颈, 2-(3-Hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic Acid, Novel Metabolite of Pyridoxal 5鈥�-Phosphate and Cysteine Is Present in Human Plasma - Chromatographic Investigations, Int. J. Mol. Sci. 21 (2020) 3548.

14. K. Morawska, N. Festinger, G. Chwatko, R. 骋艂辞飞补肠办颈, W. Ciesielski, S. Smarzewska, Rapid electroanalytical procedure for sesamol determination in real samples, Food Chem. 309 (2020) 125789.

15. P. Kubalczyk K. Purgat, P. Olejarz, I. Ko艣ka, R. 骋艂辞飞补肠办颈, Determination of homocysteine thiolactone in human urine by capillary zone electrophoresis and single drop microextraction, Anal. Biochem., 596 (2020) 113640.

16. R.M. Dyson, H.K. Palliser, N. Wilding, M.A. Kelly, G. Chwatko, R. 骋艂辞飞补肠办颈, M.J. Berry, X. Ni, I.M.R Wright, Microvascular circulatory dysregulation driven in part by cystathionine-gamma-lyase: a new paradigm for cardiovascular compromise in the preterm newborn, Microcirculation, (2019) 26: e12507.

17. K. Borowczyk, J. Piechocka, R. 骋艂辞飞补肠办颈, I. Dhar, 脴. Midtun, G.S. Tell, P.M. Ueland, O. Nyg氓rd, H. Jakubowski, Urinary Excretion of Homocysteine Thiolactone and the Risk of Acute Myocardial Infarction in Coronary Artery Disease Patients; the Western Norway B-Vitamin Intervention Trial, J. Int. Med., 285 (2019) 232-244.

18. K. Purgat, K. Borowczyk, R. Zakrzewski, R. 骋艂辞飞补肠办颈, P. Kubalczyk, Determination of nikethamide by micellar electrokinetic chromatography, Biomed. Chromatogr. 2019;33:e4571.

19. Kami艅ska, I.E. G艂owacka, B. Pasternak, R. 骋艂辞飞补肠办颈, G. Chwatko, New method for simultaneous determination of lipoyllysine and 伪-lipoic acid by high performance liquid chromatography, Bioanalysis, 11 (2019) 1359-1373.

20. G. Chwatko, M. Krawczyk, M. Iciek, A. Kami艅ska, A. Bilska-Wilkosz, B. Marcykiewicz, R. 骋艂辞飞补肠办颈, Determination of lipoic acid in human plasma by high-performance liquid chromatography with ultraviolet detection, Arab. J. Chem., 12 (2019) 4878鈥�4886.

21. J. Per艂a-Kajan, K. Borowczyk, R. 骋艂辞飞补肠办颈, O. Nyg氓rd, H. Jakubowski, Paraoxonase 1 (PON1) genotype and activity affect homocysteine thiolactone levels in humans, FASEB Journal, 32 (2018) 6019-6024.

22. M. Wro艅ska, G. Chwatko, K. Borowczyk, J. Piechocka, P. Kubalczyk, R. 骋艂辞飞补肠办颈, Application of GC-MS technique for the determination of homocysteine thiolactone in human urine, J. Chromatogr. B, 1099 (2018) 18鈥�24. P.